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3.4: Reservoir Pressure Separation At Brachial, Carotid and Radial Arteries: A Quantitative Comparison and Evaluation
Artery Research volume 20, page 54 (2017)
Abstract
Background
At present, reservoir pressure parameters are derived from arterial pressure waveforms regardless of the location of measurement. However, a comparison between sites has not been made, and site-related differences may affect interpretation. In this study, we computed reservoir pressure waveform separations on hypertensive individuals where brachial, carotid and radial pressure measurements were available and quantitatively assessed their results.
Methods
95 participants in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) had sequential measurements of pressure and flow velocity waveforms from carotid, brachial and radial arteries [1]. Pre-processing was performed to impose identical diastolic and mean blood pressures at all three arterial locations. Using pressure information only, reservoir pressure separation was performed [2, 3]. Systolic durations were estimated based on minimum pressure waveform derivatives.
Reservoir curves characterized by physiologically implausible parameters, i.e. a rate constant b < 0 or an asymptotic pressure P∞ < 0, were discarded, leaving 74 subjects with valid reservoir pressure waveforms at all three arterial locations.
Results
Estimated reservoir parameters are shown in Table 1. We observed significant differences between arteries in almost all parameters. A high correlation was observed between reservoir pulse pressure and reservoir pressure area at all locations, and the correlation between brachial and radial arteries was stronger for all parameter.
Conclusions
The results of this study indicate differences in parameters derived from reservoir pressure separation at different arterial locations. This suggests that interpretations cannot be made agnostic to the location of measurement.
References
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J. Aguado-Sierra, J. Alastruey, J.-J. Wang, N. Hadjiloizou, J. Davies, and K. H. Parker, “Separation of the reservoir and wave pressure and velocity from measurements at an arbitrary location in arteries,” Proc Inst Mech Eng Part H J Eng Med, vol. 222, no. 4, pp. 403–416, 2008.
J. E. Davies, P. Lacy, T. Tillin, D. Collier, J. K. Cruickshank, D. P. Francis, A. Malaweera, J. Mayet, A. Stanton, B. Williams, K. H. Parker, S. A. McG Thom, and A. D. Hughes, “Excess pressure integral predicts cardiovascular events independent of other risk factors in the conduit artery functional evaluation substudy of Anglo-Scandinavian Cardiac Outcomes Trial,” Hypertension, vol. 64, no. 1, pp. 60–8, Jul. 2014.
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This is an open access article distributed under the CC BY-NC license https://doi.org/creativecommons.org/licenses/by/4.0/.
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Ebner, M., Parker, K., Vercauteren, T. et al. 3.4: Reservoir Pressure Separation At Brachial, Carotid and Radial Arteries: A Quantitative Comparison and Evaluation. Artery Res 20, 54 (2017). https://doi.org/10.1016/j.artres.2017.10.034
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DOI: https://doi.org/10.1016/j.artres.2017.10.034