Table 1 Subjects characteristics (subdivided into groups according to the age)
Age group | 40~49 | 50~59 | 60~69 | ≧70 | p value for |
|---|---|---|---|---|---|
n = 1236 | n = 137 | n = 356 | n = 445 | n = 298 | trend |
Age (years) | 45 (3) | 55 (3) | 64 (3) | 76 (5) | <0.001 |
Male (male, %) | 53 (41.7) | 153 (43.7) | 207 (47.2) | 159 (55.0) | 0.002 |
Height (cm) | 162.5 (8.1) | 161.5 (8.1) | 159.5 (7.5) | 158.3 (8.2) | <0.001 |
Weight (kgw) | 64.0 (12.7) | 64.7 (10.6) | 63.0 (10.4) | 62.0 (10.9) | 0.004 |
BMI (kgw/m2) | 24.1 (3.6) | 24.7 (3.3) | 24.7 (3.3) | 24.7 (3.4) | 0.31 |
HTN (n, %) | 9 (7.1) | 76 (21.7) | 172 (39.2) | 158 (54.7) | <0.001 |
DM (n, %) | 5 (3.9) | 32 (9.1) | 78 (17.8) | 71 (24.6) | <0.001 |
Hyperlipidiemia (n, %) | 6 (4.7) | 50 (14.3) | 229 (52.2) | 144 (49.8) | <0.001 |
Creatinine (mg/dL) | 0.77 (0.45) | 0.73 (0.21) | 0.79 (0.27) | 0.93 (0.57) | <0.001 |
LDL (mg/dL) | 116.5 (34.8) | 120.0 (35.9) | 117.7 (34.1) | 113.3 (35.1) | 0.083 |
Glucose (mg/dL) | 94.5 (18.1) | 100.4 (21.2) | 104.3 (28.2) | 105.3 (26.3) | <0.001 |
Age group | 40~49 | 50~59 | 60~69 | ≧70 | p value for |
n = 1236 | n = 137 | n = 356 | n = 445 | n = 298 | trend |
Smoking (n, %) | 0.08 | ||||
Non-smoker | 95 (74.8) | 255 (72.9) | 341 (77.7) | 204 (70.6) | |
Current-smoker | 14 (11.0) | 44 (12.6) | 38 (8.7) | 14 (4.8) | |
former-smoker | 18 (14.2) | 51 (14.6) | 60 (13.7) | 71 (24.6) | |
MMSE score < 24 | 0 | 3 (0.9) | 13 (3.0) | 31 (10.8) | <0.001 |
Echocardiography variables | |||||
Ea (mmHg/ml) | 1.86 (0.44) | 1.78 (0.43) | 1.70(0.43) | 1.70 (0.53) | <0.001 |
Ees (mmHg/ml) | 4.00 (1.06) | 4.09 (1.06) | 3.67 (1.12) | 3.99 (1.73) | 0.12 |
Ea/Ees | 0.48 (0.09) | 0.45 (0.09) | 0.48 (0.12) | 0.45 (0.13) | 0.87 |
Stroke volume (ml) | 58.5 (12.3) | 64.0 (14.2) | 69.5 (14.9) | 72.5 (17.6) | <0.001 |
Cardiac index (L/min/m2) | 2.4 (0.6) | 2.6 (0.6) | 2.7 (0.6) | 2.9 (0.8) | <0.001 |
Ef (%) | 69.5 (6.2) | 70.7 (6.4) | 68.8 (7.1) | 68.5 (7.9) | 0.001 |