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High Systolic Blood Pressure is Associated with Increased Cardio-ankle Vascular Index in the Elderly

Artery Research volume 27, pages 25–31 (2021)Cite this article

Abstract

Background

Increased arterial stiffness caused by elevated Blood Pressure (BP) can be indicated by the Cardio-ankle Vascular Index (CAVI). However, the relationship between arterial stiffness and BP is complex. In addition, changes in BP may contribute to increased risk of cardiovascular disease associated with abnormal lipid profiles. So far, results from published studies have been inconclusive.

Objectives

To evaluate lipid profiles and BP, and their association with CAVI values in elderly participants.

Methods

The study included 95 elderly Thai individuals. Anthropometric data, lipid profiles, and BP and CAVI values were established. Participants were then divided into low-CAVI (CAVI < 9, n = 50) and high-CAVI groups (CAVI ≥ 9, n = 45). Stepwise linear and logistic regression models were used.

Results

The high-CAVI group had significantly higher BP and hypertension levels, than the low-CAVI group. The mean age of the high-CAVI group was also higher (≥65 years). CAVI value was positively correlated with Systolic Blood Pressure (SBP) and Pulse Pressure (PP) in the high-CAVI group. Stepwise multiple regression analysis showed SBP (β = 0.43, p < 0.01) and hip circumference (β = −0.23, p = 0.01) were associated with CAVI values. Logistic regression of the high-CAVI indices showed that the Odds Ratios (ORs) for the factors of age ≥65 years, obesity, hypertension and dyslipidemia were 7.35 (95% CI 2.42–22.36, p < 0.01), 0.20 (95% CI 0.64–0.67, p < 0.01) 4.72 (95% CI 1.67–13.32, p < 0.01), and 4.84 (95% CI 1.42–16.46, p = 0.01), respectively.

Conclusion

A higher SBP level was correlated with a high-CAVI value in elderly people.

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Authors and Affiliations

  1. Department of Basic Medical Science, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand

    Thapanee Roengrit

  2. Division of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla, Thailand

    Ruchada Sri-amad & Nawiya Huipao

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  1. Thapanee Roengrit
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  2. Ruchada Sri-amad
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Correspondence to Thapanee Roengrit.

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Peer review under responsibility of the Association for Research into Arterial Structure and Physiology

Data availability statement: The authors confirm that the data supporting the findings of this study are available within the article or its supplementary materials.

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Roengrit, T., Sri-amad, R. & Huipao, N. High Systolic Blood Pressure is Associated with Increased Cardio-ankle Vascular Index in the Elderly. Artery Res 27, 25–31 (2021). https://doi.org/10.2991/artres.k.201102.002

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  • DOI: https://doi.org/10.2991/artres.k.201102.002

Keywords

Artery Research

ISSN: 1876-4401

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