Skip to main content

The European COST Action VascAgeNet Fostering Innovation — When Industry Comes to Science

Abstract

VascAgeNet is a new European network which will join forces in order to refine, harmonize and promote the vascular ageing concept. It aims to bring innovations in cardiovascular research from bench to bedside and to establish assessment of vascular ageing in clinical practice. The interdisciplinary, inter-country and intersectional approach will enable all important players at the different stages of the innovation process to come together, as recommended in the triple or quadruple helix model of innovation, in order to guarantee best solutions. This is deemed necessary in order for economic and revolutionary solutions to be fit for wide-spread clinical use, especially in low-income and inclusiveness target countries. Thus, a clear case exists for a strong collaboration between science and industry, to foster innovations and breakthroughs in vascular ageing in order to improve clinical practice and to reduce the burden of cardiovascular diseases globally.

References

  1. Nilsson PM, Boutouyrie P, Laurent S. Vascular aging: a tale of EVA and ADAM in cardiovascular risk assessment and prevention. Hypertension 2009;54:3–10.

    Google Scholar 

  2. Laurent S, Boutouyrie P, Cunha PG, Lacolley P, Nilsson PM. Concept of extremes in vascular aging. Hypertension 2019;74:218–28.

    Google Scholar 

  3. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 2010;55:1318–27.

    Google Scholar 

  4. Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, et al. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol 2014;63:636–46.

    Google Scholar 

  5. Wu CF, Liu PY, Wu TJ, Hung Y, Yang SP, Lin GM. Therapeutic modification of arterial stiffness: an update and comprehensive review. World J Cardiol 2015;7:742–53.

    Google Scholar 

  6. Vlachopoulos C, Xaplanteris P, Aboyans V, Brodmann M, Cífková R, Cosentino F, et al. The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on peripheral circulation: endorsed by the Association for Research into Arterial Structure and Physiology (ARTERY) Society. Atherosclerosis 2015;241:507–32.

    Google Scholar 

  7. Climie RE, Mayer CC, Bruno RM, Hametner B. Addressing the unmet needs of measuring vascular ageing in clinical practice — European COoperation in Science and Technology Action VascAgeNet. Artery Res 2019. Forthcoming 2020.

  8. Merriam-Webster — Definition of innovation. Available from: https://www.merriam-webster.com/dictionary/innovation (last accessed November 28, 2019).

  9. LEAD Innovation Managament. Available from: https://www.lead-innovation.com/en/innovation-process (last accessed November 28, 2019).

  10. Dörner N, Gurtner S, Schefczyk M. Overcoming resistance to innovations: an approach for the use of communication tools within the innovation process. Int J Technol Market 2009;4: 199–216.

    Google Scholar 

  11. Kimatu JN. Evolution of strategic interactions from the triple to quad helix innovation models for sustainable development in the era of globalization. J Innov Entrepr 2016;5:16.

    Google Scholar 

  12. Etzkowitz H, Leydesdorff L. The triple helix—university-industry-government relations: a laboratory for knowledge-based economic development. EASST Rev 1995;14:14–19.

    Google Scholar 

  13. Eriksson M, Niitamo VP, Kulkki S, Hribernik KA. Living labs as a multi-contextual R&D methodology. In: 2006 IEEE International Technology Management Conference. Milan, Italy: IEEE; 2006, pp. 1–8.

  14. Rodrigues C, Melo AI. The triple helix model as inspiration for local development policies: an experience-based perspective. Int J Urban Region Res 2013;37:1675–87.

    Google Scholar 

  15. Carayannis EG, Campbell DFJ. ‘Mode 3’ and ‘Quadruple Helix’: toward a 21st century fractal innovation ecosystem. Int J Technol Manage 2009;46:201–34.

    Google Scholar 

  16. Cavallini S, Soldi R, Friedl J, Volpe M. Using the quadruple helix approach to accelerate the transfer of research and innovation results to regional growth (Consortium Progress Consulting S.r.l. & Fondazione FORMIT). Brussels: European Union; 2016.

  17. Morrow DA, de Lemos JA. Benchmarks for the assessment of novel cardiovascular biomarkers. Circulation 2007;115:949–52.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christopher C. Mayer.

Additional information

Peer review under responsibility of the Association for Research into Arterial Structure and Physiology

Rights and permissions

This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mayer, C.C., Climie, R.E., Hametner, B. et al. The European COST Action VascAgeNet Fostering Innovation — When Industry Comes to Science. Artery Res 26, 125–129 (2020). https://doi.org/10.2991/artres.k.200430.001

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2991/artres.k.200430.001

Keywords