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Hypertension: Protective Effects of Physical Exercise on Cognition Function, Arterial Function and Brain Health

Artery Research volume 25, pages 81–86 (2019)Cite this article

Abstract

Systemic Arterial Hypertension (SAH) is a chronic condition that requires clinical treatment and is associated with increased risk of cognitive impairment and dementia. Therefore, strategies with fewer side effects and less invasive procedures are required. Evidence supports that Physical Exercise (PE) has antihypertensive effects and has proven to be an efficient and complementary tool for managing hypertension, reducing cardiovascular disease risk factors, and improving cerebral perfusion in the majority of healthy populations. Much of this cardiovascular-protective effect of PE is probably due to pluripotent effects on the vasculature, including regulation of vascular tone, energy metabolism, microvascular recruitment, and endothelial function (reducing oxidative stress and preserving NO availability). These factors are speculated to work synergistically, thereby reducing systolic and diastolic blood pressure and are directly related to improved cerebrovascular function. However, few studies have specifically examined the potential positive effects of PE on the brain in hypertensive individuals. In this brief review, we discuss the potential effect of different PE modalities (aerobic, resistance, and combined) that may act as an effective preventive or therapeutic strategy for reducing blood pressure in hypertensives and, consequently, mitigate the association between hypertension, cognitive impairment and risk of dementia.

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Authors and Affiliations

  1. Department of Physical Exercise, Faculdade do Vale do Araranguá (FVA), Araranguá, Santa Catarina, Brazil

    Marinei Lopes Pedralli

  2. Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia (IC/FUC), Laboratório de Investigação clínica (LIC- IC/FUC), Porto Alegre, Rio Grande do Sul, Brazil

    Eduardo Barbosa

  3. Liga de Combate à Hipertensão de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

    Eduardo Barbosa

  4. Center for the Research and Treatment of Arterial Hypertension and Cardiovascular Risk, Internal Medicine Department, Hospital Senhora da Oliveira, Guimarães/Minho University, Portugal

    Pedro Guimarães Cunha

  5. Life and Health Science Research Institute (ICVS) and School of Medicine, University of Minho, Portugal

    Pedro Guimarães Cunha

  6. ICVS/3B’s - Portugal, Government Associate Laboratory, Braga/Guimarães, Portugal

    Pedro Guimarães Cunha

  7. PRÓ-SQUALUS-PROJETO CARCHARIAS (Organização para a Pesquisa e a Conservação de Esqualos no Brasil) - Health and Quality of Life Department, Torres, Rio Grande do Sul, Brazil

    Marinei Lopes Pedralli

  8. Grupo de Pesquisa em Ciência e Saúde Coletiva (GPCSC/FVA), Araranguá, Santa Catarina, Brazil

    Marinei Lopes Pedralli

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Pedralli, M.L., Barbosa, E. & Cunha, P.G. Hypertension: Protective Effects of Physical Exercise on Cognition Function, Arterial Function and Brain Health. Artery Res 25, 81–86 (2019). https://doi.org/10.2991/artres.k.191203.003

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Artery Research

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