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Association between Irritable Affective Temperament and Nighttime Peripheral and Central Systolic Blood Pressure in Hypertension

Artery Research volume 25, pages 41–47 (2019)Cite this article

Abstract

Background

Affective temperaments (depressive, anxious, cyclothymic, irritable and hyperthymic) have important role in psychopathology, but cumulating data support their involvement in vascular pathology, especially in hypertension as well. The aim of our study was to evaluate their associations with 24-h peripheral and central hemodynamic parameters in untreated patients who were studied because of elevated office blood pressure.

Methods

The oscillometric Mobil-O-Graph was used to measure the 24-h peripheral and central parameters. Affective temperaments, depression and anxiety were evaluated with Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire, Beck and Hamilton Anxiety Scale (HAM-A) questionnaires, respectively.

Results

Seventy four patients were involved into the study (45 men). In men after the adjustment for age, irritable affective temperament score was associated with nighttime peripheral and central systolic blood pressure (β = 1.328, std. error = 0.522, p = 0.015 and β = 1.324, std. error = 0.646, p = 0.047, respectively). In case of nighttime peripheral systolic blood pressure this association remained to be significant after further adjustment for smoking, alcohol consumption, sport activity and body mass index and became non-significant after adjustment for Beck and HAM-A scores. In case of nighttime central systolic blood pressure the association lost its significance after the adjustment for smoking, alcohol consumption and sport activity.

Conclusion

Irritable affective temperament can have an impact on nighttime peripheral and central systolic blood pressures in untreated men with elevated office blood pressure.

References

  1. Bouchard TJ. Genes, environment, and personality. Science 1994;264:1700–1.

    Google Scholar 

  2. Rihmer Z, Akiskal KK, Rihmer A, Akiskal HS. Current research on affective temperaments. Curr Opin Psychiatr 2010;23:12–18.

    Google Scholar 

  3. Akiskal KK, Akiskal HS. The theoretical underpinnings of affective temperaments: implications for evolutionary foundations of bipolar disorder and human nature. J Affect Disord 2005;85:231–9.

    Google Scholar 

  4. László A, Tabák Á, Kőrösi B, Eörsi D, Torzsa P, Cseprekál O, et al. Association of affective temperaments with blood pressure and arterial stiffness in hypertensive patients: a cross-sectional study. BMC Cardiovasc Disord 2016;16:158.

    Google Scholar 

  5. Eory A, Gonda X, Lang Z, Torzsa P, Kalman J, Kalabay L, et al. Personality and cardiovascular risk: association between hypertension and affective temperaments-a cross-sectional observational study in primary care settings. Eur J Gen Pract 2014;20:247–52.

    Google Scholar 

  6. Eory A, Rozsa S, Torzsa P, Kalabay L, Gonda X, Rihmer Z. Affective temperaments contribute to cardiac complications in hypertension independently of depression. Psychother Psychosom 2014;83:187–9.

    Google Scholar 

  7. Nemcsik J, Vecsey-Nagy M, Szilveszter B, Kolossváry M, Karády J, László A, et al. Inverse association between hyperthymic affective temperament and coronary atherosclerosis: a coronary computed tomography angiography study. J Psychosom Res 2017;103:108–12.

    Google Scholar 

  8. Vázquez GH, Tondo L, Mazzarini L, Gonda X. Affective temperaments in general population: a review and combined analysis from national studies. J Affect Disord 2012;139:18–22.

    Google Scholar 

  9. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2224–60.

    Google Scholar 

  10. Danaei G, Ding EL, Mozaffarian D, Taylor B, Rehm J, Murray CJL, et al. The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors. PLoS Med 2009;6:e1000058.

  11. Whelton PK, Carey RM, Aronow WS, Casey DE, Collins KJ, Dennison Himmelfarb C, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension 2018;71:1269–324.

    Google Scholar 

  12. Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). Eur Heart J 2018;39:3021–104.

    Google Scholar 

  13. Gaborieau V, Delarche N, Gosse P. Ambulatory blood pressure monitoring versus self-measurement of blood pressure at home: correlation with target organ damage. J Hypertens 2008;26:1919–27.

    Google Scholar 

  14. László A, Reusz G, Nemcsik J. Ambulatory arterial stiffness in chronic kidney disease: a methodological review. Hypertens Res 2016;39:192–8.

    Google Scholar 

  15. Akiskal HS, Akiskal KK, Haykal RF, Manning JS, Connor PD. TEMPS-A: progress towards validation of a self-rated clinical version of the temperament evaluation of the Memphis, Pisa, Paris, and San Diego autoquestionnaire. J Affect Disord 2005;85:3–16.

    Google Scholar 

  16. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561–71.

    Google Scholar 

  17. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 1959;32:50–5.

    Google Scholar 

  18. Franssen PM, Imholz BP. Evaluation of the Mobil-O-Graph new generation ABPM device using the ESH criteria. Blood Press Monit 2010;15:229–31.

    Google Scholar 

  19. Wei W, Tölle M, Zidek W, van der Giet M. Validation of the Mobil-O-Graph: 24 h-blood pressure measurement device. Blood Press Monit 2010;15:225–8.

    Google Scholar 

  20. Papaioannou TG, Argyris A, Protogerou AD, Vrachatis D, Nasothimiou EG, Sfikakis PP, et al. Non-invasive 24 hour ambulatory monitoring of aortic wave reflection and arterial stiffness by a novel oscillometric device: the first feasibility and reproducibility study. Int J Cardiol 2013;169:57–61.

    Google Scholar 

  21. Weber T, Wassertheurer S, Rammer M, Maurer E, Hametner B, Mayer CC, et al. Validation of a brachial cuff-based method for estimating central systolic blood pressure. Hypertension 2011;58:825–32.

    Google Scholar 

  22. Hametner B, Wassertheurer S, Kropf J, Mayer C, Eber B, Weber T. Oscillometric estimation of aortic pulse wave velocity: comparison with intra-aortic catheter measurements. Blood Press Monit 2013;18:173–6.

    Google Scholar 

  23. Protogerou AD, Argyris A, Nasothimiou E, Vrachatis D, Papaioannou TG, Tzamouranis D, et al. Feasibility and reproducibility of noninvasive 24-h ambulatory aortic blood pressure monitoring with a brachial cuff-based oscillometric device. Am J Hypertens 2012;25:876–82.

    Google Scholar 

  24. Wassertheurer S, Kropf J, Weber T, van der Giet M, Baulmann J, Ammer M, et al. A new oscillometric method for pulse wave analysis: comparison with a common tonometric method. J Hum Hypertens 2010;24:498–504.

    Google Scholar 

  25. Suarez EC, Kuhn CM, Schanberg SM, Williams RB, Zimmermann EA. Neuroendocrine, cardiovascular, and emotional responses of hostile men: the role of interpersonal challenge. Psychosom Med 1998;60:78–88.

    Google Scholar 

  26. Pope MK, Smith TW. Cortisol excretion in high and low cynically hostile men. Psychosom Med 1991;53:386–92.

    Google Scholar 

  27. Sloan RP, Bagiella E, Shapiro PA, Kuhl JP, Chernikhova D, Berg J, et al. Hostility, gender, and cardiac autonomic control. Psychosom Med 2001;63:434–40.

    Google Scholar 

  28. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996;93:1043–65.

    Google Scholar 

  29. Williams JE, Din-Dzietham R, Szklo M. Trait anger and arterial stiffness: results from the Atherosclerosis Risk in Communities (ARIC) study. Prev Cardiol 2006;9:14–20.

    Google Scholar 

  30. Hajjari P, Mattsson S, McIntyre KM, McKinley PS, Shapiro PA, Gorenstein EE, et al. The effect of hostility reduction on autonomic control of the heart and vasculature: a randomized controlled trial. Psychosom Med 2016;78:481–91.

    Google Scholar 

  31. Everson SA, Kauhanen J, Kaplan GA, Goldberg DE, Julkunen J, Tuomilehto J, et al. Hostility and increased risk of mortality and acute myocardial infarction: the mediating role of behavioral risk factors. Am J Epidemiol 1997;146:142–52.

    Google Scholar 

  32. Wong JM, Na B, Regan MC, Whooley MA. Hostility, health behaviors, and risk of recurrent events in patients with stable coronary heart disease: findings from the Heart and Soul Study. J Am Heart Assoc 2013;2:e000052.

  33. Bisol LW, Soldado F, Albuquerque C, Lorenzi TM, Lara DR. Emotional and affective temperaments and cigarette smoking in a large sample. J Affect Disord 2010;127:89–95.

    Google Scholar 

  34. Amann B, Mergl R, Torrent C, Perugi G, Padberg F, El-Gjamal N, et al. Abnormal temperament in patients with morbid obesity seeking surgical treatment. J Affect Disord 2009;118:155–60.

    Google Scholar 

  35. Pacini M, Maremmani I, Vitali M, Santini P, Romeo M, Ceccanti M. Affective temperaments in alcoholic patients. Alcohol 2009;43:397–404.

    Google Scholar 

  36. Rovai L, Maremmani AGI, Bacciardi S, Gazzarrini D, Pallucchini A, Spera V, et al. Opposed effects of hyperthymic and cyclothymic temperament in substance use disorder (heroin- or alcohol-dependent patients). J Affect Disord 2017;218:339–45.

    Google Scholar 

  37. Nemeroff CB, Goldschmidt-Clermont PJ. Heartache and heart-break—the link between depression and cardiovascular disease. Nat Rev Cardiol 2012;9:526–39.

    Google Scholar 

  38. Huffman JC, Mastromauro CA, Beach SR, Celano CM, DuBois CM, Healy BC, et al. Collaborative care for depression and anxiety disorders in patients with recent cardiac events: the Management of Sadness and Anxiety in Cardiology (MOSAIC) randomized clinical trial. JAMA Intern Med 2014;174:927–35.

    Google Scholar 

  39. Yang WY, Melgarejo JD, Thijs L, Zhang ZY, Boggia J, Wei FF, et al. Association of office and ambulatory blood pressure with mortality and cardiovascular outcomes. JAMA 2019;322:409–20.

    Google Scholar 

  40. Weber T, Wassertheurer S, Schmidt-Trucksäss A, Rodilla E, Ablasser C, Jankowski P, et al. Relationship between 24-hour ambulatory central systolic blood pressure and left ventricular mass: a prospective multicenter study. Hypertension 2017;70:1157–64.

    Google Scholar 

  41. Sarafidis PA, Loutradis C, Karpetas A, Tzanis G, Piperidou A, Koutroumpas G, et al. Ambulatory pulse wave velocity is a stronger predictor of cardiovascular events and all-cause mortality than office and ambulatory blood pressure in hemodialysis patients. Hypertension 2017;70:148–57.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Family Medicine, Semmelweis University, Budapest, Hungary

    Beáta Kőrösi, Dóra Batta & János Nemcsik

  2. Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary

    Xénia Gonda & Zoltán Rihmer

  3. Magnetic Resonance Research Center, Semmelweis University, Budapest, Hungary

    Zsófia Nemcsik-Bencze

  4. GP practice Jula/Schindler, Nuremberg, Germany

    Andrea László

  5. Department of Radiology, Heart and Vascular Center, Semmelweis University, Budapest, Hungary

    Milán Vecsey-Nagy

  6. Department of Family Medicine, Health Service of Zugló (ZESZ), Budapest, Hungary

    János Nemcsik

Authors
  1. Beáta Kőrösi
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  2. Dóra Batta
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  3. Xénia Gonda
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  4. Zoltán Rihmer
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  5. Zsófia Nemcsik-Bencze
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  6. Andrea László
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  7. Milán Vecsey-Nagy
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  8. János Nemcsik
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Corresponding author

Correspondence to János Nemcsik.

Additional information

Peer review under responsibility of the Association for Research into Arterial Structure and Physiology

Data availability statement: The LabArchives data used to support the findings of this study have been deposited in the “TEMPSA_MOB 24 h data” repository, under license and so cannot be made freely available. Requests for access to these data should be made to corresponding author.

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Kőrösi, B., Batta, D., Gonda, X. et al. Association between Irritable Affective Temperament and Nighttime Peripheral and Central Systolic Blood Pressure in Hypertension. Artery Res 25, 41–47 (2019). https://doi.org/10.2991/artres.k.191123.002

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  • DOI: https://doi.org/10.2991/artres.k.191123.002

Keywords

Artery Research

ISSN: 1876-4401

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