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Arterial Stiffness, Central Blood Pressure, and Cardiac Biomarkers in Long-Distance Walkers

Artery Research volume 25, pages 71–76 (2019)Cite this article

Abstract

The cardiovascular effects of long-distance and -duration activities and their relationship with arterial stiffness and cardiac biomarkers are still unclear. This study aimed to assess arterial stiffness and Central Blood Pressure (cBP) and correlate them with cardiac biomarkers in long-distance walkers (271 km in 4 days). This longitudinal study assessed Peripheral Systolic Blood Pressure (pSBP), Peripheral Diastolic Blood Pressure (pDBP), Central Systolic Blood Pressure (cSBP), Central Diastolic Blood Pressure (cDBP), Pulse-Wave Velocity (PWV), Central Pulse Pressure (cPP), Augmentation Index (AIx), and total vascular resistance, using the Mobil-O-Graph® device and biomarkers creatine kinase-MB, troponin T, and brain natriuretic peptide. All items were assessed 30 days before the event (A0) and at the end of the 1st (A1), 2nd (A2), 3rd (A3), and 4th (A4) days of walk. Data were analyzed using Stata Software and p-values <0.05 were considered significant. This study included 25 men, with mean age of 46 ± 10.5 years and body mass index of 20.2 ± 2.3 kg/m2. pSBP level reduced from A0 (122.8 ± 2.2) to A1 (111.6 ± 2.1) (p = 0.004) and cSBP level reduced from A0 (110.2 ± 2.2) to A1 (101 ± 1.8) (p = 0.035). CK-MB enzyme correlated with PVR in both A1 (r = 0.445, p < 0.033) and A4 (r = 0.554, p < 0.006). Troponin T showed correlation at A4 with cSBP (r = 0.468, p < 0.024) and pSBP (r = 0.470, p < 0.023). There was no change in PWV. This study showed that this exercise modality did not cause harmful alterations related to arterial stiffness behavior.

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Authors and Affiliations

  1. School of Social Sciences and Health Department, Pontifical Catholic University of Goiás, Goiás, Brazil

    Wátila Moura Sousa, Maicon Borges Euzébio & Priscila Valverde de Oliveira Vitorino

  2. Hypertension League and Post Graduation Program, Federal University of Goiás, Brazil

    Wátila Moura Sousa, Maicon Borges Euzébio, Ana Luiza Sousa, Thiago Veiga Jardim, Paulo Cesar Veiga Jardim & Weimar Kunz Sebba Barroso

  3. Hypertension Unit — Hospital Clinic, Barcelona University, Barcelona, Spain

    Antonio Coca

  4. Hospital Clínic de Barcelona, Spain

    Gonzalo Grazioli

  5. Hypertension Unit, Hypertension League, Porto Alegre, Brazil

    Eduardo Costa Duarte Barbosa

Authors
  1. Wátila Moura Sousa
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  2. Maicon Borges Euzébio
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  3. Priscila Valverde de Oliveira Vitorino
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  4. Ana Luiza Sousa
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  5. Thiago Veiga Jardim
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  6. Paulo Cesar Veiga Jardim
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  7. Antonio Coca
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  8. Gonzalo Grazioli
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  9. Eduardo Costa Duarte Barbosa
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  10. Weimar Kunz Sebba Barroso
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Corresponding author

Correspondence to Eduardo Costa Duarte Barbosa.

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Peer review under responsibility of the Association for Research into Arterial Structure and Physiology

Data availability statement: The current study data are available from the corresponding author on reasonable request.

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This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Sousa, W.M., Euzébio, M.B., de Oliveira Vitorino, P.V. et al. Arterial Stiffness, Central Blood Pressure, and Cardiac Biomarkers in Long-Distance Walkers. Artery Res 25, 71–76 (2019). https://doi.org/10.2991/artres.k.191106.002

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  • DOI: https://doi.org/10.2991/artres.k.191106.002

Keywords

Artery Research

ISSN: 1876-4401

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