- ARTERY 18 Poster Session
- Poster Session II - Special Populations II
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P155 Determinants of Pulse Wave Velocity in Children
Artery Research volume 24, page 125 (2018)
Abstract
Background
Arterial stiffening measured by Pulse Wave Velocity (PWV) predicts cardiovascular events and mortality in adults. It advances with age and seems accelerated in children with certain disease conditions such as chronic kidney disease or diabetes. The aim of this study was to determine factors that influence PWV in children.
Methods
PWV was captured in 285 children aged 10–14 years attending a Portuguese school. The effects of sex, age, height, weight, body mass index, waist circumference, blood pressure, heart rate and sodium excretion in 24-h urinary samples in PWV were tested.
Results
PWV correlated positively with age, height, systolic blood pressure, diastolic blood pressure and heart rate in males and females (p < 0.05) and with weight in males (p < 0.05). Major predictors for PWV in a multivariate regression analysis were gender, height, weight, diastolic blood pressure, heart rate and body mass index.
Conclusion
Our study found several determinants of PWV in children, some of them modifiable and interfering with cardiovascular outcomes. Future research may provide clarity to the association between PWV in children and cardiovascular events in adulthood.
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This is an open access article distributed under the CC BY-NC license https://doi.org/creativecommons.org/licenses/by/4.0/.
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Silva, C., Formigo, M., Formigo, N. et al. P155 Determinants of Pulse Wave Velocity in Children. Artery Res 24, 125 (2018). https://doi.org/10.1016/j.artres.2018.10.208
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DOI: https://doi.org/10.1016/j.artres.2018.10.208