- ARTERY 18 Poster Session
- Poster Session II - Hypertension VI
- Open access
- Published:
P124 Central Blood Pressure Measurement: Paradigm Shift
Artery Research volume 24, page 115 (2018)
Abstract
Introduction
It is estimated that currently 17 million deaths annually in the world occur due to cardiovascular disease (CV), about one third of all deaths. 9.4 million are related to arterial hypertension (HA). The use of methods that allow the early identification of structural and functional cardiovascular alterations can improve the strategy of treatment and control of these patients.
Description
LSO, 65 years old, female, white. Ringing in the ear and headache. Hypertension for 18 years and panic syndrome using Candesartan 8 mg, Fluoxetine 20 mg and Alprazolan 0.5 mg. In 06-2016, presenting blood pressure (BP):172 × 104 mmHg. Candesartan was elevated to 16 mg, initiating Rosuvastatin 10mg (C-reactive protein:16 and LDL-C:142), targeted improvement of lifestyle habits. ABPM 2 weeks after normal. Returned on 10-2017 with tachycardia and dizziness. She stopped Fluoxetine and Rosuvastatin. BP:178 × 84 mmHg. Reintroduced Fluoxetine and Rosuvastatin with new normal ABPM. Returned in 02-2018 with feeling of death, uneasiness and palpitations. BP:138 × 78 mmHg and normal ECG, in regular use of the medications. Accomplished non - invasive central blood pressure measurement (Mobil O’Graph) with arterial stiffness elevation, central AP:143 mmHg and augmentation index (AI):50 was performed. Felodipine -2.5 mg was started even with the new normal ABPM. 4 months later new measures with central BP:128 and AI = 33-table 1.
Conclusion
The treatment of HA depends on the choice of the drug and early onset with reduction of BP and CV outcomes 3,4. The central BP has greater relevance in the reduction of BP and cardiovascular outcomes than the peripheral BP 5,6. Keywords: Hypertension; Central Blood Pressure; Arterial Stiffness.
References
World Health Organization. (WHO). A global brief on hypertension: silent killer, global public health crisis. Geneva; 2013.
Pizzi Oea. Pulse wave velocity – methodology and prognostic implications in hypertension. Rev Bras Hipertensvol. 2006;13(1):59–62.
SBC. VII Diretrizes brasileiras de hipertensão arterial. Sociedade Brasileira de Cardiologia, Sociedade Brasileira de Hipertensão, Sociedade Brasileira de Nefrologia. Arq Bras Cardiol 2016; 197: 1–87.
Aronow WS. Multiple blood pressure medications and mortality among elderly individuals. JAMA 2015;313(13).
Rodrigues FB, Arantes AC, Chinem BM, Araújo YCL, Barroso WKS. Pressão Central: evidências – importância clínica. SBC on line. 2014.
Dahlof B, Devereux R, al. KSe. Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): A Randomized trial against atenolol. Lancet. 2002;359:995–63.
Author information
Authors and Affiliations
Rights and permissions
This is an open access article distributed under the CC BY-NC license https://doi.org/creativecommons.org/licenses/by/4.0/.
About this article
Cite this article
Filho, G.C.G., Sousa, W.K.S.B. P124 Central Blood Pressure Measurement: Paradigm Shift. Artery Res 24, 115 (2018). https://doi.org/10.1016/j.artres.2018.10.177
Published:
Issue Date:
DOI: https://doi.org/10.1016/j.artres.2018.10.177