- ARTERY 18 Poster Session
- Poster Session II - Hypertension VI
- Open access
- Published:
P121 Association of Cardiorespiratory Fitness with Arterial Stiffness and Peripheral and Central Blood Pressure in Resistant Hypertension Patients
Artery Research volume 24, page 114 (2018)
Abstract
Background
The relationship between arterial stiffness, blood pressure (BP) and cardiorespiratory fitness (CRF) has been studied in healthy populations and cardiovascular patients, since all of which proved to be independent predictors of all-cause mortality. We aimed to investigate the association of CRF with arterial stiffness and peripheral and central hemodynamics, in patients with resistant hypertension (RT).
Methods
In this cross-sectional study, 30 patients (13 men, 17 women; age, 57.7 ± 8.1 years; weight, 79.2 ± 11.6 kg; body mass index, 29.7 ± 4.0 kg/m2) with resistant hypertension were recruited in the Hospital Infante D. Pedro (Aveiro) and Hospital Pedro Hispano (Matosinhos). Outcome measures included CRF (VO2peak), peripheral and central BP, and carotid-femoral pulse wave velocity (cf-PWV). Correlation analysis was conducted to assess the association between variables.
Results
A significant negative correlation was found between VO2peak (33.7 ± 6.2 mLO2/kg/min) and central (141.0 ± 21.3 mmHg; r = −0.395, p = 0.031) and peripheral systolic BP (148.4 ± 21.3 mmHg; r = −0.363, p = 0.049). VO2 peak was also correlated with pulse pressure (PP) amplification ratio (1.2 ± 0.1 mmHg; r = 0.361, p = 0.050). The association with central systolic BP (r = −0.403, p = 0.035) and PP amplification ratio (r = 0.408, p = 0.033) remained significant after adjusted for age. VO2 peak showed no correlation with PWV (9.4 ± 2.9 m/s; r = −0.075, p = 0.694) and peripheral (88.1 ± 12.2 mmHg; r = −0.138 p = 0.467) and central diastolic BP (88.5 ± 12.7 mmHg; r = −0.133, p = 0.483).
Conclusion
This study confirms the inverse relationship between CRF and central systolic BP and PP amplification ratio in RH patients, regardless of age.
Author information
Authors and Affiliations
Rights and permissions
This is an open access article distributed under the CC BY-NC license https://doi.org/creativecommons.org/licenses/by/4.0/.
About this article
Cite this article
Garcia, C., Lopes, S., Bertoquini, S. et al. P121 Association of Cardiorespiratory Fitness with Arterial Stiffness and Peripheral and Central Blood Pressure in Resistant Hypertension Patients. Artery Res 24, 114 (2018). https://doi.org/10.1016/j.artres.2018.10.174
Published:
Issue Date:
DOI: https://doi.org/10.1016/j.artres.2018.10.174