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P109 Reservoir-Excess Pressure Characteristics Help Identify People with High Intra-Arterial Aortic Systolic Blood Pressure
Artery Research volume 24, page 111 (2018)
Abstract
Background
High aortic blood pressure (BP) predicts clinical outcomes beyond peripheral BP. Aortic BP may differ according to level of systolic BP (SBP)-amplification but these differences cannot be identified using current non-invasive BP measurement methods. In this study, we sought to determine if high intra-arterial aortic BP could be detected via reservoir-excess pressure characteristics.
Methods
Standard cuff BP, SphygmoCor-derived central BP (CBP), and intraarterial aortic and brachial waveforms were recorded in 160 participants (61 ±11 years, 68% male) during coronary angiography. SBP-amplification was defined as ≥5 mmHg increase in SBP across the aortic-to-brachial arteries, whereas no SBP-amplification was defined as 0.20 both). Aortic, but not brachial, reservoir pressure was significantly higher in participants with no SBP-amplification (2506 ± 662 versus 2239 ± 640 Pa/s, p = 0.011). This pattern was also observed for aortic excess pressure (718 ± 304 versus 624 ± 293 Pa/s, p = 0.049) and aortic diastolic rate constant (0.021 ± 0.08 versus 0.025 ± 0.09 s−1, p = 0.002). All differences remained after adjustment for age, sex and intra-arterial aortic SBP.
Conclusions
Reservoir-excess pressure characteristics help identify people with high intra-arterial aortic BP that are otherwise missed using cuff BP or SphygmoCor-derived CBP. Thus, analysis of BP waveforms using reservoir-excess pressure characteristics could be used to refine accuracy of BP measurement.
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This is an open access article distributed under the CC BY-NC license https://doi.org/creativecommons.org/licenses/by/4.0/.
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Stoneman, E., Picone, D., Schultz, M. et al. P109 Reservoir-Excess Pressure Characteristics Help Identify People with High Intra-Arterial Aortic Systolic Blood Pressure. Artery Res 24, 111 (2018). https://doi.org/10.1016/j.artres.2018.10.162
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DOI: https://doi.org/10.1016/j.artres.2018.10.162