P80 Analysis of Endothelial Function in Male Students in Southern Brazil: The Role of Physical Activity

Abstract

Context

School adolescents in Porto Alegre have a mean physical inactivity (PI) <300 min/week of 43%, and another 13% do not perform physical activities. In this scenario, endothelial cells that regulate vascular homeostasis by the expression of bioactive mediators may be influenced by inflammatory responses and dysfunction. To date, there is no evidence that the level of PI can influence the preservation of endothelial function in this population.

Objectives

To describe the characterization of the hemodynamic and vascular profile of adolescents and to correlate the level of PI with endothelial function.

Methods

This cross-sectional study evaluated 39 volunteer men between 12 and 18 years of age, allocated to different percentiles of body mass index, recruited from the school network. The variables collected were: anthropometry, questionnaire on the behavior of adolescents and dilation mediated by the flow of the brachial artery (FMD). Parametric data are presented as mean and standard deviation and the level of correlation between the level of PI and endothelial function was assessed by the Pearson test.

Results

Age mean was 14.5 ± 4 years, BMI percentile mean was 78.2 ± 38, PI level mean was 210.8 ± 154.7 minutes/week, and FMD mean was 9.7 ± 2.9%. At this moment, with 46% of the sample collected, we found a probability of correlation between the PI and mean arterial diameter until the peak of dilation (r = 0.41, p < 0.01) and between the PI level and time to peak (r = 0.35p < 0.05).

Conclusions

In view of the preliminary findings, these adolescents are classified as sedentary, presenting hemodynamic and endothelial damage.