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A numerical study on the application of the functionally graded bioabsorbable materials in the stent design

Artery Research volume 24, pages 1–8 (2018)Cite this article

Abstract

Background

Angioplasty with stenting is one of the primary treatment for coronary artery disease, hence, performance of the stent is deemed important. Bioabsorbable stents are the new generation of stents. Bioabsorbable magnesium alloys are a promising solution for adverse effects of long-term usage of stents. While their corrosion mechanics and biocompatibility have extensively been studied, there are no studies on application of functionally graded materials (FGM) on reduction of dogboning in bioabsorbable stents.

Methods

The objective of this study was at reducing the dogboning via the application of the FGM. A combination of the finite element (FE) method and optimization algorithm were employed to analyse/optimize the mechanical behaviour of bioabsorbable stents. Proposed FGM, in this study, was a combination of AZ80 and WE43 magnesium alloys. Dogboning of the FGM stent was chosen as objective function to be minimized and heterogeneous index was chosen as control variable in the optimization algorithm.

Results

The results revealed that the optimum FGM stent with heterogeneous index of 1.4625 has lower dogboning (63%) compared to that of the uniform stents made of AZ89 or WE43 magnesium alloy.

Conclusions

Furthermore, the results suggested that the plastic material properties have higher impact on the mechanical behaviour of the stent in comparison to the elastic material properties.

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Author information

Authors and Affiliations

  1. Mechanical Engineering Department, Sahand University of Technology, Tabriz, Iran

    Hossein Bahreinizad

  2. Basir Eye Health Research Center, Tehran, Iran

    Milad Salimi Bani

  3. Atherosclerosis Research Center, Baqiyatallah University of Medical Science, Tehran, Iran

    Arezoo Khosravi

  4. Department of Mechanical Engineering, Kyushu University, 744 Motooka, 819-0395, Nishi-ku, Fukuoka, Japan

    Alireza Karimi

Authors
  1. Hossein Bahreinizad
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  2. Milad Salimi Bani
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  3. Arezoo Khosravi
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  4. Alireza Karimi
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Corresponding author

Correspondence to Alireza Karimi.

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This is an open access article distributed under the CC BY-NC license https://doi.org/creativecommons.org/licenses/by/4.0/.

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Bahreinizad, H., Bani, M.S., Khosravi, A. et al. A numerical study on the application of the functionally graded bioabsorbable materials in the stent design. Artery Res 24, 1–8 (2018). https://doi.org/10.1016/j.artres.2018.09.001

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  • DOI: https://doi.org/10.1016/j.artres.2018.09.001

Keywords

Artery Research

ISSN: 1876-4401

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