P128: Comparison of Augmentation Index Obtained from HEM-9000AI and Mobil-O-Graph in Japanese Normotensive Individuals

Abstract

Background

HEM-9000AI (HEM) is an established device for measurement of radial augmentation index (rAIx) used by applanation tonometry in Japan. Mobil-O-Graph (MOG) is a cuff-based oscillometric device for assessment of central aortic AIx (cAIx) and the usefulness to Europeans has been reported. We compared the AIx between HEM and MOG in Japanese normoten-sive subjects.

Methods

We enrolled 106 normotensive volunteers (47 male, 21 to 79 years). The left radial arterial waveform was recorded with the HEM. MOG were taken on the left arms, which arm circumferences (ACs) were measured to allow the correct choice of cuff (two sizes available; 20–24 and 24–32 cm). We performed multiple regressions for AIx and key variables in HEM and MOG.

Results

The ACs in M and F were 25.7 ± 1.9 (mean ± SD) cm and 23.5 ± 2.1cm, respectively. Both rAIx (70.5 ± 15.3% vs 83.6 ± 11.9%, p < 0.001) and cAIx (17.2 ± 7.3% vs 29.7 ± 9.8%, p < 0.001) in M were smaller than those in F. Multiple regression analysis revealed that cAIx in M (R² = 0.5176) was significantly associated with age (β = 0.17, p = 0.004) and cuff size (p = 0.001). cAIx obtained using the smaller cuff was significantly increased compared to the larger cuff (25.1 ± 5.9% vs 14.8 ± 5.9%). In F, cAIx (R² = 0.2245) tended to be associated with age (β = 0.16, p = 0.072) and was significantly associated with height (β = −0.62, p = 0.007) and heart rate (β = −0.26, p = 0.0029).

Conclusions

The brachial cuff-based waveform recordings are useful for Japanese normotensive individuals. However, the mean AC is close to the bound of two cuff sizes and the measurement of lower cAx using the larger cuff is less sensitive.