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Effect of aldosterone antagonists on common carotid artery’s intima-media thickness, stiffness indices and flow mediated vasodilatation of brachial artery in CAD patients

References

  1. Boesby L, Elung-Jensen T, Strandgaard S, Kamper A-L. Eplerenone attenuates pulse wave reflection in chronic kidney disease stage 3–4 e a randomized controlled study. PLoS One 2013; 8(5):e64549. http://doi.org/10.1371/journal.pone.0064549.

  2. Epstein M, Duprez DA. Resistant hypertension and the pivotal role for mineralocorticoid receptor antagonists: a clinical update 2016. Am J Med 2016;129(7):661–6.

    Google Scholar 

  3. Drüppel V, Kusche-Vihrog K, Grossmann C, Gekle M, Kasprzak B, Brand E, et al. Long-term application of the aldosterone antagonist spironolactone prevents stiff endothe-lial cell syndrome. FASEB J 2013;27:3652–9.

    Google Scholar 

  4. Hwang M-H, Yoo J-K, Luttrell M, Kim H-K, Meade TH, English M, et al. Mineralocorticoid receptors modulate vascular endothelial function in human obesity. Clin Sci (Lond) 2013;125(11): 513–20.

    Google Scholar 

  5. Syngle A, Vohra K, Kaur L, Sharma S. Effect of spironolactone on endothelial dysfunction in rheumatoid arthritis. Scand J Rheumatol 2009;38(1):15–22.

    Google Scholar 

  6. Lee CJ, Park S. The role of carotid ultrasound for cardiovascular risk stratification beyond traditional risk factors. Yonsei Med J 2014;55(3):551–7.

    Google Scholar 

  7. Chang SM, Hakeem A, Nagueh SF. Predicting clinically unrecognized coronary artery disease: use of two-dimensional echocardiography. Cardiovasc Ultrasound 2009;7:10.

    Google Scholar 

  8. ACC/AHA Guidelines for Coronary Angiography. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on coronary Angiography). JACC 1999;33(6):1756–824.

    Google Scholar 

  9. Schulz KF, Altman DJ, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med 2010;152(11):1–8.

    Google Scholar 

  10. Vohra K, Krishan P, Varma S, Kalra HS. Effect of low-dose mineralocorticoid receptor antagonists on metabolic profile and endothelial dysfunction in metabolic syndrome. Diabetes Metab 2016;42:65–8.

    Google Scholar 

  11. Corretti MC, Andreson TG, Emeli J, Benjamin CD, Charbonneau F, Mark A. Guideline for ultrasound assessment of endothelial dependent flow mediated vasodilation of the brachial artery. J Am Coll Cardiol 2002;39:257–65.

    Google Scholar 

  12. Cipolli JAA, Ferreira-Sae MC, Martins RP, Pio-Magalhães JA, Bellinazzi VR, Matos-Souza JR, et al. Relationship between serum uric acid and internal carotid resistive index in hypertensive women: a cross-sectional study. BMC Cardiovasc Disord 2012;12:52–7.

    Google Scholar 

  13. Fichtlscherer S, Rössig L, Breuer S, Vasa M, Dimmeler S, Zeiher AM. Tumor necrosis factor antagonism with etanercept improves systemic endothelial vasoreactivity in patients with advanced heart failure. Circulation 2001;104:3023–5.

    Google Scholar 

  14. Lovisi JC, Ezequiel DA, Costa MB, Bicalho TC, Barros FC, Souza Gdo C, et al. Espironolactone improves flow-mediated vasodilatation in subjects with the metabolic syndrome. J Bras Nefrol 2011;33(4):463–6.

    Google Scholar 

  15. Syngle A, Vohra K, Khichi D, Garg N, Verma I, Kaur L. Spironolactone improves endothelial dysfunction in ankylosing spondylitis. Clin Rheumatol 2013;32(7):1029–36.

    Google Scholar 

  16. Garg R, Kneen L, Williams GH, Adler GK. Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects. Diabetes Obes Metab 2014; 16(3):268–72.

    Google Scholar 

  17. Sola S, Mir MQS, Cheema FA, Khan-Merchant N, Menon RG, Parthasarathy S, et al. Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome. Circulation 2005;111:343–8.

    Google Scholar 

  18. Vohra K, Krishan P, Varma S, Kalra HS. Exploring the potential of low dose sulfasalazine in stable coronary artery disease patients: randomized, double blind, placebo controlled study. Eur Heart J Cardiovasc Pharmacother 2015;1:214–6.

    Google Scholar 

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Correspondence to Krishan Pawan.

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Kanchan, V., Pawan, K., Sudhir, V. et al. Effect of aldosterone antagonists on common carotid artery’s intima-media thickness, stiffness indices and flow mediated vasodilatation of brachial artery in CAD patients. Artery Res 18, 69–72 (2017). https://doi.org/10.1016/j.artres.2017.04.005

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