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A new statistical phase offset technique for the calculation of in vivo pulse wave velocity

Artery Research volume 13, pages 17–27 (2016)Cite this article

Abstract

Pulmonary blood pressure measurements were collected from 5 clinically healthy horses. Pulse wave velocity (PWV) values were calculated using five techniques, four existing (minimum foot-to-foot, F2F; maximum 1st derivative, M1D; maximum 2nd derivative, M2D; and cross correlation, CC) and the new statistical phase offset technique (SPO). The SPO technique was also applied to systolic (SPO-S), diastolic (SPO-D) and full wave (SPO-FW) data. The reliability of each analysis technique was determined using the consistency of calculated PWV values.

Using the original data sets, of variable length (2 ≤ n ≤ 5) due to the effects of respiration, the SPO technique gave the most consistent results (SPO-D, 2.31 ± 0.31 m/s; SPO-S, 2.18 ± 0.30 m/s; and SPO-FW, 2.45 ± 0.35 m/s). The CC technique, was complex to implement but also gave considerable consistency (CC, 2.64 ± 0.36 m/s). The family of techniques utilizing only a single point of comparison all provided less consistent results (M1D, 2.82 ± 0.56 m/s; M2D, 2.90 ± 1.09 m/s; and F2F, 3.42 ± 1.67 m/s).

Consistent length data sets were then created (n = 5) and analyzed. Results were: SPO-S, 2.74 ± 0.34 m/s; SPO-D, 2.67 ± 0.40 m/s; SPO-FW, 2.78 ± 0.36 m/s; F2F, 2.53 ± 0.52 m/s; M1D, 3.39 ± 1.28 m/s; M2D, 3.20 ± 1.90 m/s; and CC, 3.23 ± 0.40 m/s.

Comparison of the results indicate that of the techniques included in this study, the new SPO technique provided the greatest reliability for determining PWV values. It was also intuitive to implement.

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Authors and Affiliations

  1. School of Engineering, University of Guelph, N1G 1P1, Guelph, ON, Canada

    John Runciman & Martine McGregor

  2. Dept. of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada

    John Runciman, Gonçalo Silva, Gabrielle Monteith, Laurent Viel & Luis G. Arroyo

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  1. John Runciman
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  2. Martine McGregor
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  3. Gonçalo Silva
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  4. Gabrielle Monteith
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  5. Laurent Viel
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  6. Luis G. Arroyo
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Correspondence to John Runciman.

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Runciman, J., McGregor, M., Silva, G. et al. A new statistical phase offset technique for the calculation of in vivo pulse wave velocity. Artery Res 13, 17–27 (2016). https://doi.org/10.1016/j.artres.2015.12.001

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  • DOI: https://doi.org/10.1016/j.artres.2015.12.001

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Artery Research

ISSN: 1876-4401

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