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HIV and atherosclerosis: Heterogeneity of studies results

Artery Research volume 7, pages 81–83 (2013)Cite this article

References

  1. Palios J, Ikonomidis I, Lekakis J, Anastasiou-Nana M. Atherosclerotic vascular disorders in HIV infected patients. Artery Res 2011;5:81–90.

    Google Scholar 

  2. Hsue PY, Lo JC, Franklin A, Bolger AF, Martin JN, Deeks SG, et al. Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. Circulation 2004 Apr 6; 109(13): 1603–8.

    Google Scholar 

  3. Hsue PY, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, et al. Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses. AIDS 2006 Nov 28; 20(18): 2275–83.

    Google Scholar 

  4. Ross AC, Rizk N, O’Riordan MA, Dogra V, El-Bejjani D, Storer N, et al. Relationship between inflammatory markers, endothelial activation markers, and carotid intima-media thickness in HIV-infected patients receiving antiretroviral therapy. Clin Infect Dis 2009 Oct 1; 49(7): 1119–27.

    Google Scholar 

  5. Papita A, Albu A, Fodor D, Itu C, Cârstina D. Arterial stiffness and carotid intima-media thickness in HIV infected patients. Med Ultrason 2011;13(2):127–34.

    Google Scholar 

  6. Charakida M, Donald AE, Green H, Storry C, Clapson M, Caslake M, et al. Early structural and functional changes of the vasculature in HIV-infected children: impact of disease and antiretroviral therapy. Circulation 2005 Jul 5; 112(1): 103–9.

    Google Scholar 

  7. Johnsen S, Dolan SE, Fitch KV, Kanter JR, Hemphill LC, Connelly JM, et al. Carotid intimal medial thickness in human immunodeficiency virus-infected women: effects of protease inhibitor use, cardiac risk factors, and the metabolic syndrome. J Clin Endocrinol Metab 2006 Dec;91(12): 4916–24.

    Google Scholar 

  8. Lorenz MW, Stephan C, Harmjanz A, Staszewski S, Buehler A, Bickel M, et al. Both long-term HIV infection and highly active antiretroviral therapy are independent risk factors for early carotid atherosclerosis. Atherosclerosis 2008 Feb; 196(2): 720–6.

    Google Scholar 

  9. Giuliano Ide C, de Freitas SF, de Souza M, Caramelli B. Subclinic atherosclerosis and cardiovascular risk factors in HIV-infected children: PERI study. Coron Artery Dis 2008 May; 19(3):167–72.

    Google Scholar 

  10. Bongiovanni M, Casana M, Cicconi P, Pisacreta M, Codemo R, Pelucchi M, et al. Predictive factors of vascular intima media thickness in HIV-positive subjects. J Antimicrob Chemother 2008 Jan;61(1):195–9.

    Google Scholar 

  11. Currier JS, Kendall MA, Zackin R, Henry WK, Alston-Smith B, Torriani FJ, et al., AACTG 5078 Study Team. Carotid artery intima-media thickness and HIV infection: traditional risk factors overshadow impact of protease inhibitor exposure. AIDS 2005 Jun 10; 19(9): 927–33.

    Google Scholar 

  12. Kaplan RC, Kingsley LA, Gange SJ, Benning L, Jacobson LP, Lazar J, et al. Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men. AIDS 2008 Aug 20; 22(13): 1615–24.

    Google Scholar 

  13. Grunfeld C, Delaney JA, Wanke C, Currier JS, Scherzer R, Biggs ML, et al. Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study. AIDS 2009 Sep 10; 23(14): 1841–9.

    Google Scholar 

  14. Freire CM, Ribeiro AL, Barbosa FB, Nogueira AI, de Almeida MC, Barbosa MM, et al. Comparison between automated and manual measurements of carotid intima-media thickness in clinical practice. Vasc Health Risk Manag 2009;5:811–7.

    Google Scholar 

  15. Wong M, Edelstein J, Wollman J, Bond MG. Ultrasonic-pathological comparison of the human arterial wall. Verification of intima-media thickness. Arterioscler Thromb 1993; 13(4):482–6.

    Google Scholar 

  16. Oliviero U, Bonadies G, Apuzzi V, Foggia M, Bosso G, Nappa S, et al. Human immunodeficiency virus per se exerts atherogenic effects. Atherosclerosis 2009 Jun;204(2):586–9.

    Google Scholar 

  17. Bonnet D, Aggoun Y, Szezepanski I, Bellal N, Blanche S. Arterial stiffness and endothelial dysfunction in HIV-infected children. AIDS 2004 Apr 30; 18(7): 1037–41.

    Google Scholar 

  18. Lekakis J, Tsiodras S, Ikonomidis I, Palios J, Poulakou G, Rallidis L, et al. HIV-positive patients treated with protease inhibitors have vascular changes resembling those observed in atherosclerotic cardiovascular disease. Clin Sci (Lond) 2008 Sep;115(6): 189–96.

    Google Scholar 

  19. Solages A, Vita JA, Thornton DJ, Murray J, Heeren T, Craven DE, et al. Endothelial function in HIV-infected persons. Clin Infect Dis 2006 May 1 ;42(9): 1325–32.

    Google Scholar 

  20. Nolan D, Watts GF, Herrmann SE, French MA, John M, Mallal S. Endothelial function in HIV-infected patients receiving protease inhibitor therapy: does immune competence affect cardiovascular risk? QJM 2003 Nov;96(11):825–32.

    Google Scholar 

  21. Dubé MP, Shen C, Mather KJ, Waltz J, Greenwald M, Gupta SK. Relationship of body composition, metabolic status, antiretroviral use, and HIV disease factors to endothelial dysfunction in HIV-infected subjects. AIDS Res Hum Retroviruses 2010; 26(8):847–54.

    Google Scholar 

  22. Lebech AM, Kristoffersen US, Wiinberg N, Kofoed K, Andersen O, Hesse B, et al. Coronary and peripheral endothelial function in HIV patients studied with positron emission tomography and flow-mediated dilation: relation to hypercholesterolemia. Eur J Nucl Med Mol Imaging 2008 Nov;35(11): 2049–58.

    Google Scholar 

  23. Shankar SS, Dubé MP, Gorski JC, Klaunig JE, Steinberg HO. Indinavir impairs endothelial function in healthy HIV-negative men. Am Heart J 2005 Nov; 150(5):933.

    Google Scholar 

  24. Dubé MP, Gorski JC, Shen C. Severe impairment of endothelial function with the HIV-1 protease inhibitor indinavir is not mediated by insulin resistance in healthy subjects. Cardiovasc Toxicol 2008 Mar;8(1):15–22.

    Google Scholar 

  25. Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, et al. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS 2009 Sep 24; 23(15): 2021–7.

    Google Scholar 

  26. Stein JH, Klein MA, Bellehumeur JL, McBride PE, Wiebe DA, Otvos JD, et al. Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation 2001 Jul 17; 104(3):257–62.

    Google Scholar 

  27. Dubé MP, Shen C, Greenwald M, Mather KJ. No impairment of endothelial function or insulin sensitivity with 4 weeks of the HIV protease inhibitors atazanavir or lopinavir-ritonavir in healthy subjects without HIV infection: a placebo-controlled trial. Clin Infect Dis 2008 Aug 15; 47(4): 567–74.

    Google Scholar 

  28. Grubb JR, Dejam A, Voell J, Blackwelder WC, Sklar PA, Kovacs JA, et al. Lopinavir-ritonavir: effects on endothelial cell function in healthy subjects. J Infect Dis 2006 Jun 1 ; 193(11 ): 1516–9.

    Google Scholar 

  29. Torriani FJ, Komarow L, Parker RA, Cotter BR, Currier JS, Dubé MP, et al., ACTG 5152s Study Team. Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: the ACTG (AIDS Clinical Trials Group) Study 5152s. J Am Coll Cardiol 2008 Aug 12; 52(7): 569–76.

    Google Scholar 

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Authors and Affiliations

  1. Cardiology IV Unit, Niguarda Ca Granda Hospital, Milano-Bicocca University, Piazza Ospedale, Maggiore 3, 20162, Milano, Italy

    Cristina Giannattasio

  2. Internal Medicina Department, San Gerardo Hospital, Monza, Italy

    Alessandro Maloberti

  3. Infectious Disease Department, San Gerardo Hospital, Monza, Italy

    Andrea Gori

Authors
  1. Cristina Giannattasio
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  2. Alessandro Maloberti
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  3. Andrea Gori
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Correspondence to Cristina Giannattasio.

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Giannattasio, C., Maloberti , A. & Gori, A. HIV and atherosclerosis: Heterogeneity of studies results. Artery Res 7, 81–83 (2013). https://doi.org/10.1016/j.artres.2013.02.001

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