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Vascular function is impaired early after the initiation of chronic cigarette smoking

Abstract

Background

The aim of this study was to assess resistance artery function in short-term chronic cigarette smokers and non-smoking control subjects.

Methods

Reactive hyperemia was assessed in 19 cigarette smokers (age 23 ± 1 years) and 19 non-smokers (age 23 ± 1 years).

Results

Cigarette smokers demonstrated a 23% lower peak forearm blood flow response compared with non-smokers (15.81 ± 0.66 vs. 20.58 ± 1.26 mL/min/100 mL, p < 0.05) and a 22% lower area under the curve of the reactive hyperemia response (607 ± 51.57 vs. 775 ± 53.51 mL/min/100 mL × 3 min, p < 0.05).

Conclusions

These results indicate that smoking-induced impairments of vascular function occur early after the initiation of chronic cigarette smoking.

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Correspondence to Brian R. Weil.

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This is an open access article distributed under the CC BY-NC license. https://doi.org/creativecommons.org/licenses/by/4.0/

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Weil, B.R., Byrne, S.A., Baynard, T. et al. Vascular function is impaired early after the initiation of chronic cigarette smoking. Artery Res 3, 111–114 (2009). https://doi.org/10.1016/j.artres.2009.06.025

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  • DOI: https://doi.org/10.1016/j.artres.2009.06.025

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