Table 2 Baseline characteristics of the study population according to the tertile of the Gensini score
Variables | Low GS (GS < 24, n = 178) | Medium GS (GS:24–47, n = 193) | High GS (GS ≥ 48, n = 180) | P value |
|---|---|---|---|---|
General conditions | ||||
Male, n (%) | 96 (53.93%) | 127 (65.8%) | 132 (73.33%) | 0.001 |
Age (years) | 63 (56, 71) | 63 (53, 71) | 64 (54, 70) | 0.732 |
BMI (kg/m2) | 24.51 (23.5, 25.78) | 25 (24.06, 26.61) | 25.71 (24.77, 27.3) | < 0.001 |
STD, n (%) | 110 (61.8%) | 133 (68.91%) | 151 (83.89%)*# | |
LVEF (%) | 59 (58, 62) | 59 (57, 61) | 58 (56, 60) | 0.011 |
Risk factors, n (%) | ||||
HTN, n (%) | 145 (81.46%) | 162 (83.94%) | 162 (90%)*# | 0.065 |
DM, n (%) | 49 (27.53%) | 63 (32.64%) | 67 (37.22%)*# | 0.147 |
Smoking, n (%) | 49 (27.53%) | 70 (36.27%) | 67 (37.22%)*# | 0.1 |
Drinking, n (%) | 28 (15.73%) | 37 (19.17%) | 37 (20.56%) | 0.48 |
Laboratory test | ||||
TC (mmol/dl) | 3.94 (3.09, 4.66) | 3.82 (3.2, 4.44) | 3.64 (2.91, 4.47) | 0.262 |
TG (mmol/dl) | 1.22 (0.91, 1.83) | 1.56 (1.09, 2.01) | 1.26 (0.97, 1.72) | 0.001 |
LDL-C (mmol/dl) | 2.5 (1.91, 2.95) | 2.56 (2.02, 2.87) | 2.7 (2.17, 3.16) | 0.026 |
sdLDL-C (mmol/dl) | 0.55 (0.41, 0.78) | 0.61 (0.43, 0.84) | 0.51 (0.38, 0.72)*# | 0.029 |
HDL-C (mmol/dl) | 1.15 (0.95, 1.34) | 1.12 (0.94, 1.25) | 1.08 (0.9, 1.2)*# | 0.002 |
Hb (g/dl) | 137 (128, 147) | 133 (123.5, 145) | 134 (121, 144) | 0.019 |
Prealbumin (mg/dl) | 290.5 (246, 317) | 273 (227, 319) | 262.5 (219, 297) | 0.003 |
Albumin (g/dl) | 43 (40.4, 45.8) | 42.7 (40.4, 45.3) | 41.2 (38.7, 45.3) | 0.004 |
A/G | 1.7 (1.5, 2) | 1.74 (1.5, 1.9) | 1.6 (1.4, 1.8)*# | 0.014 |
FBG (mmol/dl) | 5.5 (4.93, 6.33) | 5.53 (5, 6.85) | 6.05 (5.21, 6.98) | 0.044 |
HbA1c (%) | 5.93 (5.6, 6.4) | 6 (5.6, 6.8) | 6.1 (5.6, 7.29) | 0.175 |
ABPM | ||||
Average SBP (mmHg) | 126.19 ± 13.07 | 126.64 ± 13.76 | 128.27 ± 14.18 | 0.315 |
Average DBP (mmHg) | 73 (69, 79) | 71 (67, 79) | 72 (67, 79.25) | 0.144 |
Average HR (bpm) | 71 (66, 78) | 71 (65, 77) | 70 (64, 74) | 0.176 |
Average MAP (mmHg) | 89 (85, 97) | 90 (84, 96) | 90 (85, 99) | 0.749 |
Awake SBP (mmHg) | 126 (117, 135) | 128 (119, 135) | 129 (120.75, 138.25) | 0.266 |
Awake DBP (mmHg) | 74 (68.25, 81) | 72 (68, 81) | 74 (67, 80) | 0.389 |
Awake HR (bpm) | 72 (68, 79) | 73 (67, 79) | 71.5 (66, 77) | 0.203 |
Awake MAP (mmHg) | 90 (85, 98.75) | 91 (85, 97) | 92 (85, 99) | 0.888 |
Nocturnal SBP (mmHg) | 124 (112, 133) | 126 (116, 135) | 128 (116.75, 137) | 0.041 |
Nocturnal DBP (mmHg) | 71 (64.25, 79) | 70 (63, 77) | 69 (63, 77) | 0.103 |
Nocturnal HR (bpm) | 64.5 (59, 71) | 66 (61, 72) | 65 (58, 70.25) | 0.053 |
Nocturnal MAP (mmHg) | 90 (80, 96) | 88 (81, 95) | 88.5 (81, 96) | 0.703 |
Night-time dipping (%) | 3.74 (− 1.2, 9.8) | 2.9 (− 2.2, 8.22) | 2.33 (− 2.8, 8.37) | 0.688 |
Morning surge (mmHg) | 25.56 ± 11.57 | 21.65 ± 12.82 | 26.71 ± 14.21 | < 0.001 |
Average PP (mmHg) | 49 (43, 55) | 53 (45, 60) | 55 (46.75, 61)* | < 0.001 |
AASI | 0.41 (0.36, 0.47) | 0.49 (0.43, 0.58) | 0.53 (0.45, 0.62)*# | < 0.001 |