Table 1 Baseline characteristics of the study population
Variables | Total (N = 619) | Control group (n = 68) | CAD group (n = 551) | P value |
|---|---|---|---|---|
General conditions | ||||
Male, n (%) | 395 (63.81%) | 40 (58.82%) | 355 (64.43%) | 0.364 |
Age (years) | 62 (54, 70) | 57 (54.75, 64.25) | 63 (54, 70) | 0.004 |
BMI (kg/m2) | 25.1 (24.02, 26.61) | 24.52 (22.84, 25.75) | 25.24 (24.09, 26.82) | 0.001 |
STD, n (%) | 429 (69.31%) | 35 (51.47%) | 394 (71.51%) | 0.001 |
LVEF (%) | 59 (57, 61) | 60 (59, 62) | 59 (57, 61) | < 0.001 |
Risk factors, n (%) | ||||
HTN, n (%) | 517 (83.52%) | 48 (70.59%) | 469 (85.12%) | 0.002 |
DM, n (%) | 189 (30.53%) | 10 (14.71%) | 179 (32.49%) | 0.003 |
Smoking, n (%) | 203 (32.79%) | 17 (25%) | 186 (33.76%) | 0.147 |
Drinking, n (%) | 112 (18.09%) | 10 (14.71%) | 102 (18.51%) | 0.442 |
Laboratory test | ||||
TC (mmol/dl) | 3.85 (3.14, 4.56) | 4.13 (3.55, 4.87) | 3.82 (3.08, 4.53) | 0.016 |
TG (mmol/dl) | 1.35 (0.97, 1.86) | 1.22 (0.88, 1.69) | 1.36 (0.98, 1.93) | 0.052 |
LDL-C (mmol/dl) | 2.54 (2.02, 2.96) | 2.36 (1.94, 2.58) | 2.57 (2.03, 2.99) | 0.001 |
sdLDL-C (mmol/dl) | 0.55 (0.4, 0.79) | 0.55 (0.4, 0.74) | 0.54 (0.4, 0.79) | 0.728 |
HDL-C (mmol/dl) | 1.12 (0.94, 1.29) | 1.25 (1.04, 1.53) | 1.11 (0.93, 1.27) | < 0.001 |
Hb (g/dl) | 135 (124, 145) | 135.5 (128, 145) | 135 (124, 145) | 0.29 |
Prealbumin (mg/dl) | 275 (231, 316) | 289.5 (240.25, 315.75) | 273 (230, 316) | 0.253 |
Albumin (g/dl) | 42.6 (40, 45.8) | 44.3 (41.45, 47.53) | 42.45 (39.62, 45.48) | < 0.001 |
A/G | 1.7 (1.5, 1.9) | 1.8 (1.58, 2) | 1.7 (1.49, 1.9) | 0.005 |
FBG (mmol/dl) | 5.55 (5, 6.69) | 5.14 (4.75, 5.85) | 5.66 (5.07, 6.82) | < 0.001 |
HbA1c (%) | 5.9 (5.6, 6.8) | 5.7 (5.42, 6.06) | 6 (5.6, 6.9) | < 0.001 |
ABPM | ||||
Average SBP (mmHg) | 126 (117, 135) | 118.5 (113, 128) | 127 (118, 136) | < 0.001 |
Average DBP (mmHg) | 72 (67, 79) | 72 (66, 78) | 72 (67, 79) | 0.601 |
Average HR (bpm) | 70 (65, 76) | 68.5 (65, 76) | 71 (65, 76.5) | 0.089 |
Average MAP (mmHg) | 90 (84, 97) | 88 (82, 95) | 90 (85, 97) | 0.02 |
Awake SBP (mmHg) | 127 (117, 135) | 120.5 (115, 128) | 128 (118, 136) | < 0.001 |
Awake DBP (mmHg) | 73 (68, 80) | 74 (67.75, 79) | 73 (68, 81) | 1 |
Awake HR (bpm) | 72 (67, 79) | 70.5 (67, 77.5) | 72 (67, 79) | 0.199 |
Awake MAP (mmHg) | 90 (85, 97.5) | 89.5 (82, 94.25) | 91 (85, 98) | 0.06 |
Nocturnal SBP (mmHg) | 125 (112, 134) | 116 (106.75, 124.5) | 126 (114, 135) | < 0.001 |
Nocturnal DBP (mmHg) | 70 (63, 78) | 69.5 (60, 76) | 70 (63, 78) | 0.108 |
Nocturnal HR (bpm) | 65 (59, 71) | 61 (55, 68.25) | 65 (59.5, 71) | 0.003 |
Nocturnal MAP (mmHg) | 88 (80.5, 95) | 84.5 (76, 91.25) | 88 (81, 96) | 0.001 |
Night-time dipping (%) | 3.33 (− 2.15, 9.38) | 5.96 (0, 10.61) | 2.9 (− 2.17, 9.09) | 0.03 |
Morning surge (mmHg) | 24.4 ± 12.93 | 23.03 ± 11.73 | 24.57 ± 13.08 | 0.355 |
Average PP (mmHg) | 53 (45, 60) | 46 (42, 53) | 53 (45, 60) | < 0.001 |
AASI | 0.46 (0.39, 0.57) | 0.32 (0.24, 0.41) | 0.47 (0.4, 0.58) | < 0.001 |