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Table 1 Patient demographics

From: Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19

Male sex, n (%)

All patients (n = 34)

Ward patients (n = 14)

ICU patients (n = 20)

p-value

 

n#

 

n#

 

n#

 

22

(64.7)

 

8

(57.1)

 

14

(70.0)

 

0.34b

Age, years

63

 ± 11

 

65

 ± 13

 

62

 ± 10

 

0.42c

BMI, (kg/m2)

27.4

[24.6–31.4]

 

27.8

[24.6–36.6]

 

26.9

[24.6–30.3]

 

0.37d

Smoking, n (%)

3

(11.5)

26

1

(8.3)

12

2

(14.3)

14

0.56b

Comorbidities, n (%)

          

 Diabetes mellitus II

12

(35.3)

 

2

(14.3)

 

10

(50.0)

 

0.035b

  Metformin

7

(21.9)

32

1

(7.1)

 

6

(30.0)

18

0.087b

  Insulin

2

(6.3)

32

0

(0.0)

 

2

(10.0)

18

0.31b

  SGLT2-inhibitors

2

(6.3)

32

0

(0.0)

 

0

(0.0)

18

–

  SU-derivatives

2

(6.3)

32

0

(0.0)

 

2

(10.0)

18

0.31b

 Hypertension

15

(44.1)

 

5

(35.7)

 

10

(50.0)

 

0.41a

  Beta blocker

8

(25.0)

32

5

(35.7)

 

3

(15.0)

18

0.21b

  Diuretics

8

(25.0)

32

3

(21.4)

 

5

(25.0)

18

0.50b

  Calcium channel blockers

3

(9.4)

32

0

(0.0)

 

3

(15.0)

18

0.17b

  ACE-inhibitors

7

(21.9)

32

3

(21.4)

 

4

(20.0)

18

0.65b

  Angiotensin II receptor blockers

4

(12.5)

32

3

(21.4)

 

1

(5.0)

18

0.21b

 Chronic kidney disease

3

(8.8)

 

2

(14.3)

 

1

(5.0)

 

0.37b

Complications, n (%)

          

 AKI

11

(32.4)

 

0

(0.0)

 

11

(55.0)

 

0.001b

 ARDS

20

(58.8)

 

0

(0.0)

 

20

(100.0)

 

 < 0.001a

Mechanical ventilation, days

14

[10–21]

 

–

  

14

[10–21]

  

Days between symptom onset and admission sample

9

 ± 5

 

9

 ± 6

 

9

 ± 4

 

0.89c

Ward stay, days

–

  

8

[6–13]

 

7*

[5–16]

 

–

ICU stay, days

–

  

–

  

16

[12–23]

 

–

Total hospital stay, days

15

[10–24]

 

8

[6–13]

 

20

[14–29]

 

 < 0.001d

90-day mortality,

n (%)

11

(32.4)

 

0

(0.0)

 

11

(55.0)

 

0.001b

  1. Values represent frequencies, means ± standard deviation, or median with interquartile range
  2. ICU intensive care unit, BMI body mass index, SGLT2 sodium glucose transport protein 2, SU sulfonylurea, ACE angiotensin converting enzyme, AKI acute kidney injury, ARDS acute respiratory distress syndrome
  3. aChi-square test,
  4. bFisher’s exact test,
  5. cindependent samples T-test,
  6. dMann–Whitney U test,
  7. #deviating number of patients due to missing data,
  8. *ward stay after discharged from ICU