Skip to main content
  • Poster Abstract Presentations
  • Open access
  • Published:

P9.13 A Study on Ambulatory Measurement of Central Hemodynamics on Healthy Individuals with no Cardiovascular Risk Factors



Central blood pressure (BP) parameters arise as a novel tool in clinical practice. Mounting evidence demonstrates that central systolic BP has a closer correlation with target organ damage and a stronger value for predicting cardiovascular events. However, data regarding ambulatory measurement of central BP parameters and pulse wave velocity (PWV) are scarce including both healthy individuals and patients at risk for cardiovascular disease. In the latter group, a recent study has shown that central BP falls during night but less compared to peripheral BP. We sought to investigate whether this phenomenon is also observed in healthy individuals.


We recruited 50 healthy volunteers and performed 24h ambulatory measurement of PWV and central systolic BP using the validated Mobil-O-graph device.


As expected, PWV correlated with 24 hour mean peripheral and central BP. However the strongest correlation presented between day PWV and day systolic BP (r=0.441, p=0.001). In addition, PWV decreased significantly during night following both peripheral and central BP (p<0.001). We also observed that central systolic BP exhibits a similar dipping profile compared to peripheral systolic BP but to a significant lesser degree (p=0.001).


The 24h ambulatory measurement of central hemodynamics provides important information regarding central BP and PWV. Central systolic BP decreases similarly, though at a smaller scale, compared with peripheral BP throughout the night, a phenomenon observed in both healthy individuals and patients at cardiovascular risk. Whether this phenomenon is a physiological response or an index of vascular pathology remains to be further investigated.

Author information

Authors and Affiliations


Rights and permissions

This is an open access article distributed under the CC BY-NC license

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lazaridis, A., Papadopoulou, E., Varouktsi, A. et al. P9.13 A Study on Ambulatory Measurement of Central Hemodynamics on Healthy Individuals with no Cardiovascular Risk Factors. Artery Res 8, 157 (2014).

Download citation

  • Published:

  • Issue Date:

  • DOI: