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P2.4 Feasibility of Aortic Arch Mechanics - A Study in Normal Subjects


There are no data in the literature regarding aortic arch mechanics assessed with 2D speckle tracking (2D-ST) echocardiography.


To study the feasibility of measuring vascular mechanics in the aortic arch with 2D-ST echocardiography and to define normal values.


We recruited 54 healthy volunteers and performed a complete echocardiographic exam. We included in the analysis a short axis view of the aortic arch, after the emergence of the brachiocephalic artery. The 2D-ST methodology was used to off-line calculate aortic arch mechanics (EchoPAQ, GE Healthcare®). The analysis was performed for circumferential aortic strain (CAS) and for early circumferential aortic strain rate (eCASR). We assessed the aortic pulse wave velocity (PVW) with the Complior®. Kolmogorov-Smirnov test was used for normality assessment.


We included 50 controls with a gender balance and a mean age of 33±9 years. Of the total 300 aortic wall segments, 278 had adequate waveforms for analysis. Global CAS had a normal distribution (p = 0.20); the mean and median CAS were 11.3±3.2% and 11.5% (8.4–13.7) respectively. Global eCASRalso had a normal distribution (p = 0.10); the mean and median eCASR were 1.5±0.4 s-1 and 1.6 s-1 (1.3–1.7), respectively. There was a significant negative correlation between CAS, age (r=-0.46, p<0.01), pulse pressure (r=-0.40, p<0.01), PWV (r=-0.52, p = 0.03) and the vascular augmentation index (r=-0.60, p = 0.01). A similar association was identified for eCARS.


2D-ST is a feasible methodology for the analysis of the aortic arch mechanics; in this study, we obtained reference values and normal distributions.

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Teixeira, R., Pereira, T., Monteiro, R. et al. P2.4 Feasibility of Aortic Arch Mechanics - A Study in Normal Subjects. Artery Res 8, 133–134 (2014).

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