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PO-25 Left Ventricular End-Systolic Elastance (Ecavi) Estimated with CAVI

Abstract

Objective

Left ventricular end-systolic elastance (Ecavi)was estimated using the parameters measured for calculating cardio-ankle vascular index (CAVI).

Methods

Participants comprised 4,954 healthy individuals (2,679 males, 2,275 females) who visited the health examination center at Fukui-ken Saiseikai Hospital between July 2007 and November 2013. Left ventricular-arterial coupling (Ees/Ea) was obtained from end-systolic arterial pressure (Pes), end-diastolic arterial pressure (Pd), pre-ejection period (PEP) and ejection time (ET), all of which were obtained as parameters measured on a vascular screening system (VaSera VS-1500N; Fukuda Denshi, Tokyo, Japan) based on the non-invasive method described by Hayashi et al.(1). Mean arterial pressure (Pm) was assumed to be equal to Pes for the calculation of Ees/Ea(2) in this study. Ees/Ea was assumed as the balance of stiffness between the end-systolic left ventricle and aorta. Left ventricular end-systolic elastance estimated with CAVI was defined as CAVI × Ees/Ea.

Results

The population showed the same results as the healthy group recruited in the user’s manual of the vascular screening system (Fig. 1); namely, normal range of CAVI was between 6.3 and 8.7, CAVI was higher in males than in females, and CAVI was slightly increased in the high aged group. Mean and standard deviation of Ecavi were 9.3 and 4.5, respectively, in all age groups, and in both males and females (Fig. 2).

Conclusion

The original left ventricular end-systolic elastance (Ees) could be estimated as Ecavi, representing CAVI × Ees/Ea, using a non-invasive vascular screening system.

Average of CAVI in Healthy Group.

Average of Ecavi in Healthy Group.

References

  1. Hayashi K. et al., Anesthesiology, 2000;92:1769–76.

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  2. Takaku A. et al., Proc of 11th Annual Meeting Tokai-Hokuriku Branch JSA, 2013;11:Q01–1.

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Yoshikawa, H., Yamasaki, N., Kobashi, K. et al. PO-25 Left Ventricular End-Systolic Elastance (Ecavi) Estimated with CAVI. Artery Res 8, 175 (2014). https://doi.org/10.1016/j.artres.2014.09.031

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  • DOI: https://doi.org/10.1016/j.artres.2014.09.031