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Collaterals in right and left coronary dominance



Collateral coronary flow may protect patients against myocardial ischemia. There is no data regarding the difference in collateral development in relationship to coronary dominance and potential influence on outcome. We aimed to investigate whether there is a relationship between coronary dominance, collateral development and influence on outcome.


The study population comprised all patients with single vessel disease and right or left coronary dominance (RD or LD), with a proximal stenosis above 90%. Demographic, clinical and angiographic data were compared in patients with RD and LD, as well as outcome.


More patients with ST elevation myocardial infarction (STEMI) and RD demonstrated collaterals compared to LD (51% vs. 26%, p = 0.042) and had a higher Rentrop score (1.5 ± 0.6 vs. 1.0 ± 0, p < 0.05). Fewer patients died in the RD group (9% vs. 26% in the LD group, p = 0.018). In patients without STEMI, there was a tendency to more collateral development in the RD group (although this difference became significant in patients with totally occluded vessels 80% in RD vs. 57% in LD, p < 0.05). In addition, in this group of patients without STEMI, (as in the STEMI group), there were fewer deaths in the RD group over the study period (6% vs 18% in the LD group, p < 0.01).


Patients with single vessel disease and RD develop more collaterals than those with LD, and have a better outcome. In addition, in individuals with STEMI and single vessel disease with collaterals, those with RD have a higher Rentrop score.


  1. Freedman SB, Dunn RF, Bernstein L, Morris J, Kelly DT. Influence of coronary collateral blood flow on the development of exertional ischemia and Q wave infarction in patients with severe single-vessel disease. Circulation 1985; 71: 681–6.

    Google Scholar 

  2. Rogers WJ, Hood WP, Mantle JA, Baxley WA, Kirklin JK, Zorn GL, et al. Return of left ventricular function after reperfusion in patients with myocardial infarction: importance of subtotal stenosis or intact collaterals. Circulation 1984; 69: 338–49.

    Google Scholar 

  3. Sabia PJ, Powers ER, Ragosta M, Sarembock IJ, Burwell LR, Kaul S. An association between collateral blood flow and myocardial viability in patients with recent myocardial infarction. N Engl J Med 1992; 327: 1825–31.

    Google Scholar 

  4. Ilia R, Carmel S, Cafri C, Gueron M. Coronary collaterals in patients with normal and impaired left ventricular systolic function. Int J Cardiol 1998; 63(2): 151–3.

    Google Scholar 

  5. Gorlin R. Coronary anatomy. Major Probl Intern Med 1976; 11: 40–58.

    Google Scholar 

  6. Veltman CE, de Graaf FR, Schuijf JD, van Werkhoven JM, Jukema JW, Kaufmann PA, et al. Prognostic value of coronary vessel dominance in relation to significant coronary artery disease determined with non-invasive computed tomography coronary angiography. Eur Heart J 2012; 33(11): 1367–77.

    Google Scholar 

  7. Rentrop KP, Cohen M, Blanke H, Phillips RA. Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol 1985; 5: 587–92.

    Google Scholar 

  8. Ilia R, Cafri C, Weinstein JM, Gueron M. Acute myocardial infarction due to occlusion of the dominant left circumflex artery proximally. Am J Cardiol 2003; 92(1): 54–5.

    Google Scholar 

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Correspondence to Reuben Ilia.

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Ilia, R., Weinstein, J.M., Dray, E.M. et al. Collaterals in right and left coronary dominance. Artery Res 8, 205–208 (2014).

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