P.019 Carotid-Radial Pulse Wave Velocity During the Tests on Reactive Hyperemia in Patients with Isolated Systolic and Systolic-Diastolic Arterial Hypertension

Abstract

Purpose

To evaluate the influence of tests on reactive hyperemia on peripheral vessel’s elasticity in patients with isolated systolic (ISH) and systolic-diastolic arterial hypertension (SDH).

Methods

Patients with ISH (n=67) and SDH (n=75) similar in sex and age were examined. Two tests on reactive hyperemia were conducted. The first test included 5-minute cuff occlusion (CO), the second one — sublingual taking of 0.5 mg Nitroglycerin (NG). Carotid-radial pulse wave velocity (PWV-cr, “PulseTracePWV”, Great Britain) was measured before and after the cuff decompression or 5 minutes after Nitroglycerin taking in CO and NG tests respectively. The PWV-cr dynamics was assessed by Wilcoxon criteria.

Results

The initial PWV-cr was significantly higher in patients with SDH in relation to ISH (10.3 and 9.8 m/s respectively; p<0.05). The PWV-cr dynamics during the functional tests is presented in the table below.

Table 1

During the functional tests PWV-cr exhibited a regular decrease in both groups due to the vessel’s relaxation. But in cases of ISH it decreased to a lesser extent.

Conclusion

So we can suggest that ISH as compared with SDH was characterized by lesser tonus and depressed reactivity of upper-limb peripheral arteries.